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  • CHOOSE TARGETED 50+ SUPPORT. With targeted strains of Bifidobacterium, this formula works to provide comprehensive support to help keep you healthy as you age by supporting your immune function, bone and joint health, mental and emotional well-being, weight management, and colon and digestive health.

    DIGEST WITH EASE. This formula includes scientifically studied strains of Bifidobacteria to support the digestive needs of adults ages 50 and up, including digestive issues like gas, bloating, and irregularity. PRO-Bifido supports a healthy balance of flora in your gut and colon so your system can function at its very best.

    LIVE MORE HEALTHY DAYS. Probiotics help make short-chain fatty acids, which support overall health and immune function. In fact, 80% of your immune system is in your gut and your friendly flora play a big role in supporting this foundation of health.

    SUPPORT YOUR MOOD AND ENERGY LEVELS. Fatigue and irritability are often a result of poor vitamin and nutrient absorption. PRO-Bifido helps create a microenvironment inside your digestive system that supports full mineral absorption so you can finally feel like your happy, energetic, and vibrant self.

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    GET 15 TIMES MORE SURVIVABILITY THAN WITH VEGGIE CAPSULES. With a patented delivery method, the probiotic organisms in this formula are released over an 8-10 hour period so they bypass your stomach acids and reach deep into your intestinal tract alive (where they are needed most) so you can experience the benefits that probiotics have to offer.

  • 7 Targeted Probiotic Strains. With targeted strains of Bifidobacterium, this formula supports your immune function, bone and joint health, mental and emotional well-being, weight management, and colon and digestive health. 

    Only Once per Day. That’s it. Because with time-release delivery, the benefits are being delivered deep inside your gut hour by hour.

    Long Shelf Life & No Refrigeration Necessary. With the patented LiveBac® manufacturing process, we offer a guaranteed, extended shelf life with zero refrigeration. Many probiotics don't provide a date of any kind because their organisms die so quickly after being manufactured.

    Premium Probiotic Supplement. This formula is vegetarian, non-GMO, and free of dairy, gluten, and yeast. There is also no soy, sugar, nuts, artificial flavors, artificial colors, or preservatives.

    3 Billion Colony Forming Units per BIO-tract® pearl – which is equivalent to 45 Billion CFU (colony forming units) of standard probiotic capsules!

    Made in the USA. Our probiotics are manufactured in Washington and Colorado in facilities that are GMP certified through NSF. We adhere to the strictest quality control and FDA guidelines and perform rigorous testing on every lot to ensure they are survivable and as the label states.

    PRO-Bifido does not contain any strains that are not resident to the human gut, like Soil Based Organisms (SBOs) or active yeasts.

    The Science Behind the Survivability

    Hyperbiotics PRO-Bifido has 15x More Survivability than Capsules.

    Let us explain…

    Probiotics help replenish the beneficial gut bacteria that may have been depleted as a result of modern life and they help support overall health and well-being.

    However, studies show that without protection most probiotics entering the stomach won't survive to reach optimal sites within the gastrointestinal tract. Most probiotic products retain only 4% of these sensitive organisms during passage through the stomach's harsh environment.

    The good news: with the patented BIO-tract® protection and time-release delivery, we have increased this number to a remarkable 60%.

    The BIO-tract® Difference

    When the tablet is moistened by gastric fluids, a gel matrix forms that creates a protective layer, shielding beneficial organisms from stomach acids and directing them to release later in their journey.

    Once inside the gastrointestinal tract, probiotics begin to release at consistent levels from the tablet core, delivering a potent percentage of our living organisms throughout the day and throughout your gut, traveling deep into your intestinal tract where they are needed most.

    This is the only controlled-release delivery available for probiotics on the market today and is patented in 31 countries (US Patent 8,007,777 and 7,150,623).

    BIO-tract® vs. Enteric Coated and Veggie Capsules

    Most probiotic supplements are in veggie capsules that offer no protection from a harsh stomach environment, meaning that many of the beneficial organisms do not survive long enough to deliver the full benefit.

    Enteric coated probiotic capsules offer some protection from stomach acids with a few drawbacks. Most enteric coatings are made of a synthetic chemical that the capsule is then dipped into. In addition to unwanted added chemicals, the capsule contains air and the coating contains moisture that may be detrimental to the probiotic organisms. You see, freeze-dried probiotic powder is ‘hygroscopic,’ meaning that it seeks out moisture. The beneficial flora will start wicking the moisture away from the air and the coating, which may start killing the living probiotics inside. Essentially, the air inside both veggie capsules and enteric coated capsules can cause the living organisms inside to self-destruct, leading to a far less potent product.

    Instead of a coating or a capsule, we tablet our formulas using a patented manufacturing process called LiveBac® and a patented delivery method called BIO-tract®, which provide protection for the beneficial flora while on the shelf (as there is minimal air and moisture) and as the tablet travels through the harsh environment of your stomach acids. Simply put, this leads to greater probiotic delivery to your gut, and potentially greater health benefits for you. Furthermore, BIO-tract® ensures that the active organisms are released slowly over an 8-10 hour period while making the journey through the intestinal tract, successfully bypassing your stomach acids so that they can colonize in your small and large intestine, where you need them.

    Hyperbiotics formulas have a guaranteed, extended shelf life with zero refrigeration.

    † At the time of manufacture.

    ‡ Patented BIO-tract® delivery method consistently delivers as many as 15 times, or more, the number of live, viable probiotic organisms past simulated stomach acids than veggie capsules as demonstrated through in vitro lab testing.

  • A shelf life you can count on. We use a patented manufacturing process called LiveBac® that increases the stability of PRO-Bifido without refrigeration and enables us to guarantee its shelf life until the date of expiration found on the bottom of your bottle.

    Store in a cool, dry place. Really. If you don't live in a cool, dry place or keep your home below 78 degrees, it is best to store your bottle in the fridge or even better, in the freezer, when/if you can. PRO-Bifido is only susceptible to extreme heat and humidity once the bottle has been opened (our probiotics are very well protected until then). PRO-Bifido has a guaranteed, extended shelf life with zero refrigeration.

    It's OK to take on an empty stomach (though not required). Our patented BIO-tract® delivery ensures that the living organisms are delivered throughout your day and throughout your gut – so you don't need to buffer it with food as you may with other capsules.

    Use earlier rather than later. The reason we never have too many tablets per bottle at Hyperbiotics is that CFUs begin to slowly die off once the bottle is opened (this applies to all probiotics, not just PRO-Bifido. In fact, our patented technology makes our die-off drastically slower than that of others!). We want you to get the highest potency possible, so we simply don't pack hundreds of tablets into one bottle.

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    Increase your dosage when needed. If you are looking for a more intense approach to probiotic supplementation or have just completed a round of antibiotics, you can take 2-3 tablets each day. It's also a good idea to increase your dosage just before and during travel as it often exposes you to added digestive and immune stress.

    Recycle your bottle when you're done. We're committed to minimizing our ecological footprint, and we'd love for you to join us by recycling your empty bottle whenever possible. In fact, we're taking action to reduce negative impacts on our planet's natural resources and improve ecosystems around the world.

    An additional tip is to eat a whole food diet, high in fruits and vegetables. Studies show that the microorganisms in our gut change relatively quickly based on the food we eat. Foods that are rich in prebiotics will also help your probiotics colonize and “set up shop” in your GI tract.

    When you combine a clean, whole diet with probiotic supplementation, you are giving your body the tools it needs to find its balance. Make sure to stay hydrated and to stay as active as you can so that your body can move out the unnecessary as your probiotic colonies are being repopulated.

  • What strains are in PRO-Bifido?
    PRO-Bifido contains the following probiotic strains:
    • Bifidobacterium infantis
    • Bifidobacterium bifidum
    • Bifidobacterium breve
    • Bifidobacterium lactis
    • Bifidobacterium longum
    • Lactobacillus plantarum
    • Lactobacillus acidophilus

    What are the benefits of taking PRO-Bifido?
    Getting more Bifidobacteria into your system is one of the best things you can do for yourself as a mature adult.

    PRO-Bifido replenishes crucial Bifidobacterium—often depleted in the digestive tract due to aging, diet, stress, and certain medications—and helps mature adults by:

    • Supporting bone and joint health
    • Supporting colon and digestive health
    • Helping you absorb the nutrients from your food and vitamins
    • Supporting your immune system
    • Maintaining your energy levels
    • Supporting weight management

    Hyperbiotics Glucose Support

    How many CFU (colony forming units) does PRO-Bifido provide?
    Each PRO-Bifido slow-release tablet provides 3 billion CFU with 2 strains of Lactobacillus and 5 targeted strains of Bifidobacterium to support regularity and a healthier system, so you can feel better and more energized every day.

    Can I take PRO-Bifido in addition to another probiotic formula like PRO-15?
    Absolutely. If you are over 50, we recommend that you take PRO-Bifido daily. For even more digestive support, you could take it alongside PRO-15, PRO-15 Advanced Strength, and/or Hyperbiotics Immune. We also highly recommend that you consider adding PRO-Dental to your regimen to support your ENT and dental health.

    Does PRO-Bifido contain any soil-based organisms (SBOs) or active yeasts?
    At Hyperbiotics, we are dedicated to using beneficial strains resident only to the human digestive tract. Our formulas do not contain SBOs or active yeasts.

    How quickly can I expect to feel a difference?
    Probiotics are much like vitamins–some people notice a difference almost immediately while others may need a few weeks or more. It’s also possible to simply notice a subtle shift in a healthier direction. From the day you start taking PRO-Bifido, it gets to work colonizing in your digestive tract.

    How long should I take a probiotic?
    We believe that taking a probiotic on a daily basis is one of the most proactive things that you can do to support your immune and digestive health. Because aspects of modern life can continuously deplete the beneficial bacteria in the gut, we suggest taking probiotics daily over the course of several months or more.

    Do I need to refrigerate these?
    With patented LiveBac®, we are able to guarantee our formulas with zero refrigeration–so you can be confident that your probiotics are viable when you take them.

    Will my probiotics survive being shipped in the heat?
    Yes! LiveBac® enables our products to withstand extreme heat for up to seven days – even longer if both seals are left intact.

    Need help understanding the microbiome?
    Check out our Microbiome Glossary to learn more about this world beneath the microscope.

    Have additional questions? We’ve got answers! View our complete FAQ list here!

  • • U.S. orders: We offer FREE standard shipping on all U.S. orders over $39, which takes 3-8 business days for order processing and shipping. We also offer FREE expedited shipping for orders over $100. Expedited shipping takes 2-6 business days for order processing and shipping.
    If your order is less than $39, you may choose standard shipping for $5 or expedited shipping for $8. 

    • International Orders (outside of the USA): We offer a flat fee of $9 for a fully-tracked shipping method to the countries listed below. For countries not on the list, we can ship via an untrackable shipping method for $9.50.
    Please note we are not responsible for duties, taxes, or customs clearance in your country.
    Please check your local requirements before placing your order.

    Czech Republic
    New Zealand
    Saudi Arabia
    South Korea
    United Arab Emirates
    United Kingdom
  • "I love this brand of probiotics. They are so easy to swallow and really help aid digestion. I have purchased the PRO-15 and the ones for urinary health and have had great results. I purchased these for my mom since she has been having digestive problems and these have been amazing at helping get her back to being herself. Even I have seen a difference in her mood and can tell she is feeling better. I think it is great that this brand really targets the specific needs of different ages and different digestive issues." - Becca

    "I LOVE this product, I have taken many, many probiotics which I actually never noticed a difference in how I felt. With PRO-Bifido, I have become regular, my skin more supple and an overall better gut feel!!! GREAT PRODUCT!" - Kevi C.

    "I bought this product for my mother who suffers from celiac disease. She has a hard time finding products that are gluten-free that keep her regular. I myself am a Hyperbiotics fan for their other products and so I decided to buy PRO-Bifido for my mother. Let me just tell you! WOW! My mom said her digestion and energy have increased exponentially after taking it. Her mood has also improved (I'm being cautiously optimistic lol). Now my dad (who's 55) has started taking it too and he says he feels great! We are hooked! I highly recommend you try it!" - Amazon Customer

    "Bought this after having my Biome checked, which revealed that Bifido was THE bacteria missing in my gut. After years of trying different probiotics/prebiotics, brewing my own Kombucha, babysitting my gut bacteria, FINALLY scored a complete and total win with this. Life changing. Have your biome checked and buy your probiotic based on what you need and then look for a Hyperbiotics probiotic that fills the need, this brand has delivered." - Amazon Customer

    "I love this product so much. I had to take antibiotics for 3 oral surgeries over the past 13 months so my stomach was a mess! This product has been part of my wellness and recovery plan, as well as fermented foods and eating lots of veggies. Thanks for the educational handbook that you sent me too! It was very interesting and helpful. Keep on creating these awesome products for us." - NC_firefly

    "Before PRO-Bifido I was having inconsistent bowel issues as well as allergy headaches on a daily basis. Since taking the PRO-Bifido my bathroom habits are much better and I only experience occasional headaches. Great product especially for anyone who has histamine issues." - Amazon Customer

    "My mom was needing a new probiotic, as the one she was taking prior was making her feel bloated. Even after a couple of weeks she noticed a world of a difference and told me that she felt great and didn't have to worry about being gassy. Everyone's body is different, but this one worked great for her. It is great that this brand provides targeted support for people over 50, I think that is what made the difference." - Nicloe

  • We are dedicated to you and your journey toward greater health.
    We expect you will love our formulas. If for some reason you don’t, you are protected by our no-questions-asked, money back guarantee!

    Our 100% Money Back Guarantee
    We will go above and beyond to help you however we can. Just say the word if you’re not fully satisfied—for any reason—and we’ll replace your bottle for another formula or we’ll fully refund your purchase. No questions asked.

    You have everything to gain and absolutely nothing to lose.