Skip to content

Gut-Brain Balance: Probiotic Support For Healthy Mood & Stress Response*

4 reviews
Hyperbiotics Gut-Brain Balance is uniquely designed to support healthy mood and stress response with 6 Targeted Probiotic Strains with Suntheanine to help support your mood, memory, focus, and immune function.* Each Patented Time Release Tablet has 15X more survivability than Veggie Capsules.


GET 15 TIMES MORE SURVIVABILITY THAN WITH VEGGIE CAPSULES. With a patented delivery method, the probiotic organisms in this formula are released over an 8-10 hour period so they bypass your stomach acids and reach deep into your intestinal tract alive (where they are needed most) so you can experience the benefits that probiotics have to offer.

FOCUS WITH EASE. Whether for school, work, or just everyday life, being able to concentrate and focus on the task at hand is of the utmost importance. Gut-Brain Balance combines six targeted probiotic strains with Suntheanine® (L-theanine) to harness the power of the gut-brain axis to support concentration, memory, cognitive focus, learning performance, and mental clarity.

MELT AWAY STRESS. Theanine is the natural component of green tea that brings about a sense of relaxation, a key factor in successful concentration. Gut-Brain Balance contains a pure form of the amino acid L-theanine to promote an alert state of relaxation and gently soothe away tension while reducing stress and supporting both focus and quality sleep.

STIMULATE YOUR MOOD. In addition to the relaxing properties of Suntheanine®, Gut-Brain Balance is formulated with probiotic strains that help support the production of brain chemicals in the gut (like serotonin, GABA, and dopamine) and encourage a positive, calm emotional state.

BE WELL. Did you know that 80% of your immune system is in your gut? Prioritizing your microbial health not only helps give your immune system the support it needs to keep you feeling great; it also helps maintain hormone levels, supports digestion and nutrient absorption, and encourages healthy weight management. Plus, Gut-Brain Balance  contains L. plantarum (DSM 6595), which has been clinically studied to support immune health.

Buy probiotics


6 Targeted Strains specifically chosen for the benefits they provide to both cognitive and overall health, including supporting mood, memory, focus, immune function, digestion, and regularity.

Relaxation and Concentration Support from Suntheanine®, clinically studied to promote relaxation without drowsiness, help reduce stress, and improve focus and mental clarity.

Prebiotic Fiber for Extra Support. Probiotics need nutrition from specific types of fiber to thrive. Our formula contains 100mg of FOS to help probiotics colonize and take up residence within your intestinal tract, so they can give you the support you need to stay focused.

Long Shelf Life & No Refrigeration Necessary. With the patented LiveBac® manufacturing process, we offer a guaranteed, extended shelf life with zero refrigeration. Many probiotics don't provide a date of any kind because their organisms die so quickly after being manufactured.

Premium Probiotic Supplement. This formula is vegetarian, non-GMO, and free of dairy, gluten, and yeast. There is also no soy, sugar, iron, nuts, artificial flavors, artificial colors, or preservatives.

6 Billion Colony Forming Units† per BIO-tract® caplet, which is equivalent to 90 billion CFU (colony forming units) of standard probiotic capsules!‡

Only Once per Day. That's it. Because with timed-release delivery, the benefits are being delivered deep inside your gut hour by hour.

Made in the USA. Our probiotics are manufactured in Washington and Colorado in facilities that are GMP certified through NSF. We adhere to the strictest quality control and FDA guidelines and perform rigorous testing on every lot to ensure they are survivable and as the label states.

Gut-Brain Balance does not contain any strains that are not resident to the human gut, like Soil Based Organisms (SBOs) or active yeasts.

The Science Behind the Survivability

Hyperbiotics Gut-Brain Balance Has 15x More Survivability Than Capsules.

Let us explain…

Probiotics help replenish the beneficial gut bacteria that may have been depleted as a result of modern life and they help support overall health and well-being.

However, studies show that without protection most probiotics entering the stomach won't survive to reach optimal sites within the gastrointestinal tract. Most probiotic products retain only 4% of these sensitive organisms during passage through the stomach's harsh environment.

The good news: with the patented BIO-tract® protection and time-release delivery, we have increased this number to a remarkable 60%.

The BIO-tract® Difference

When the tablet is moistened by gastric fluids, a gel matrix forms that creates a protective layer, shielding beneficial organisms from stomach acids and directing them to release later in their journey.

Once inside the gastrointestinal tract, probiotics begin to release at consistent levels from the tablet core, delivering a potent percentage of our living organisms throughout the day and throughout your gut, traveling deep into your intestinal tract where they are needed most.

This is the only controlled-release delivery available for probiotics on the market today and is patented in 31 countries (US Patent 8,007,777 and 7,150,623).

BIO-tract® vs. Enteric Coated and Veggie Capsules

Most probiotic supplements are in veggie capsules that offer no protection from a harsh stomach environment, meaning that many of the beneficial organisms do not survive long enough to deliver the full benefit.

Enteric coated probiotic capsules offer some protection from stomach acids with a few drawbacks. Most enteric coatings are made of a synthetic chemical that the capsule is then dipped into. In addition to unwanted added chemicals, the capsule contains air and the coating contains moisture that may be detrimental to the probiotic organisms. You see, freeze-dried probiotic powder is ‘hygroscopic,’ meaning that it seeks out moisture. The beneficial flora will start wicking the moisture away from the air and the coating, which may start killing the living probiotics inside. Essentially, the air inside both veggie capsules and enteric coated capsules can cause the living organisms inside to self-destruct, leading to a far less potent product.

Instead of a coating or a capsule, we tablet our formulas using a patented manufacturing process called LiveBac® and a patented delivery method called BIO-tract®, which provide protection for the beneficial flora while on the shelf (as there is minimal air and moisture) and as the tablet travels through the harsh environment of your stomach acids. Simply put, this leads to greater probiotic delivery to your gut, and potentially greater health benefits for you. Furthermore, BIO-tract® ensures that the active organisms are released slowly over an 8-10 hour period while making the journey through the intestinal tract, successfully bypassing your stomach acids so that they can colonize in your small and large intestine, where you need them.

Hyperbiotics formulas have a guaranteed, extended shelf life with zero refrigeration.

Gut-Brain Balance

Customer Reviews
5.0 Based on 4 Reviews
5 ★
4 ★
3 ★
2 ★
1 ★
Write a Review Ask a Question

Thank you for submitting a review!

Your input is very much appreciated. Share it with your friends so they can enjoy it too!

Filter Reviews:
Marlo D.
United States United States

All is Well with your Guts

I will continue with GBX! It truly makes a difference.

United States United States

The best!

I’ve tried a few of the hyperbiotics’ probiotics, this is the one that has given me the best results. At 62 and with many years of digestive issues, it was great when I found Hyperbiotics and I am very pleased with all the products that I have purchased. This formula really keeps my digestive track balanced and working properly! Thx

Christine F.
United States United States

This Stuffs Amazing!!!!!

I was soooo desperate to find something for my ADD other than Ritalin or another pharmaceutical. I have been looking for a microbiome ADD gut healing product and I finally found this!!! It works great for my ADD!!! It also lifted the brain fog I've been having which was a HUGELY EXCELLENT SIDE EFFECT!!! I tell everyone about this!!! Yay!

A Hyperbiotics Customer
Summer B.
United States United States

Love this product!!!

Increases my focus and energy while improving my gut; love it!