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hyperbiotics PRO-15 bottle

Hyperbiotics PRO-15: Uniquely Formulated to Repopulate Your Gut

15 Broad Spectrum Strains (including Lactobacillus, Bifidobacterium and Streptococcus) to effectively counter the nuking effects of today’s broad spectrum antibiotics.

5 Billion Colony Forming Units per BIO-tract® pearl+  which is equivalent to 75 Billion CFU (colony forming units) of normal probiotic capsules++!

Easy to Swallow. This tiny pearl is the smallest on the market. No wasted fillers, just micro packed goodness. You’re welcome.

Naturally Derived Prebiotic included in each pearl to help feed the probiotic for increased potency and effectiveness. Prebiotics are basically fibers that encourage the growth of beneficial bacteria throughout your colon.

Long Shelf Life & No Refrigeration Necessary. With a proprietary BIO-tract® manufacturing process, we offer a guaranteed shelf life of 18 months. At Hyperbiotics, we are committed to offering only the freshest probiotics and guarantee that your new bottle is good for at least 1 year. If you would like to know your bottle’s exact date of expiration, please email us with your bottle’s Lot Number (found on the bottom).

Only Once per Day. That’s it. Because with time-release technology, the full benefits are being delivered deep inside your gut hour by hour.

Made in USA & 100% Natural. At Hyberbiotics, we don’t believe in additives of any kind.

Vegetarian; Non-GMO and Yeast Free; No Lactose, No Soy, No Iron, No Gluten, No Wheat, No Nuts, No Chemicals, No Preservatives, No Sugar, No Artificial Colors, No Artificial Flavors.

The Science Behind the Superiority

Hyperbiotics PRO-15 is 15x More Effective than Capsules++.

Our formula reaches deep into your intestinal tract alive. Other’s don’t. Let us explain…

Gas, bloating, constipation, weakened immune system, malabsorption of nutrients, candida overgrowth and other health + digestive problems affect many of us on a regular basis.

Probiotics help restore the beneficial gut bacteria that may have been depleted as a result of stress, aging, poor diet, antibiotics, food poisoning, travelers’ diarrhea or infection and promote overall health and well-being.

However, studies show that without protection most probiotics entering the stomach won’t survive to reach optimal sites within the gastrointestinal tract. Most powders, liquids, capsules and even cultured dairy products retain only 4% of these sensitive organisms during passage through the stomach’s harsh environment. The good news: with the patented BIO-tract® protection and time-release technology, we have increased this number to a remarkable 60%.

hyperbiotics vs. capsules

The BIO-tract® Difference

hyperbiotics PRO-15 is 15 times more effective than capsules
When the pearl capsule is moistened by fluids in the stomach, the patented gel matrix creates a protective layer, shielding beneficial organisms from stomach acids and directing them to release later in their journey.

Once inside the gastrointestinal tract, probiotics begin to release at consistent levels from the pearl core, delivering a potent percentage of our living organisms throughout the day and throughout your gut, traveling deep into your intestinal tract where they are needed most. This is the only controlled-release technology available for probiotics on the market today and is patented in 31 countries (US Patent 8,007,777 and 7,150,623).


Finally, you can experience the full benefits that probiotics have to offer!



Top Strains Included in Hyperbiotics PRO-15

  • L. fermentum – Identified as highly antimicrobial and antioxidative. Helps inhibit the growth of harmful bacteria, yeast and other pathogens and has demonstrated clinical efficacy within immune health.
  • L. acidophilus – Creates a fortress of good colonies that helps keep unwanted organisms out of your gut. Studies show that L. acidophilus helps to reduce occasional diarrhea and enhances your immune system and may help to reduce cholesterol levels. Studies have shown that those taking L. acidophilus experienced significantly more relief from their gastrointestinal discomfort than did those taking a placebo.
  • L. casei – Along with L. Acidolphilus, converts lactose into lactic acid, helping those who are lactose intolerant. Helps to encourage the growth of other beneficial bacteria.
  • B. longum – Assists in breaking down carbohydrates and fighting free radicals. Provides potent antioxidant support and helps to reduce the effects of seasonal allergens.
  • B. lactis – Helps decrease H. pylori and helps the production of the front line cells in your immune system.
  • L. rhamnosus – The leading defense for travelers. Helps reduce occurrences of traveler’s diarrhea and food poisoning.
  • L. plantarum – Secretes the antioxidant hydrogen peroxide which acts as a weapon to protect your body from disease. Creates a healthy barrier in your colon and helps lower luminal pH, creating an unfavorable environment for the growth of pathogens including molds, yeasts and bacteria.
  • B. Infantis – Has been shown to reduce the major symptoms of gastrointestinal disorders, including diarrhea, flatulence, bloating, cramping and constipation. It is particularly popular as a means of combating Irritable Bowel Syndrome (IBS) and has been shown to improve digestion and the body’s ability to absorb and process nutrients.

BIO-Tract vs. Enteric Coated and Non-Enteric Coated

Normal, non-enteric coated probiotics offer no protection from a harsh stomach environment, meaning that many do not survive long enough to deliver any benefit.


Enteric coated probiotics offer protection from stomach acids with a few drawbacks. First, the organisms are released at one time, in your upper stomach and don’t often make the journey to your small or large intestine. However, the biggest reason for concern is that most enteric coatings are made of a synthetic chemical that the capsule is dipped in. Apart from unwanted added chemicals, the coating contains moisture and air that is detrimental to the probiotic organisms. You see, probiotic powder is ‘hygroscopic’, meaning that it seeks out moisture. The probiotic capsule will start whicking the moisture away from the coating which starts killing the living probiotics inside. Essentially, the enteric coating causes the capsule to self-destruct.

Now you understand the reasons why most capsules that do not require refrigeration also do not have an expiration date. Shelf stability is simply too poor.

Hyperbiotics PRO-15 is 100% naturally derived with a guaranteed shelf life of 18 months.

PRO-15 Vs. Soil Based Organisms (SBOs)

Hyperbiotics PRO-15 strains are lactobacilli and bifidobacteria. They are not soil-based organisms (SBOs), and let us explain why:


Lactobacilli and bifidobacteria are resident bacteria in the human GI tract – meaning they colonize and take up residence. SBOs, on the other hand, are transient micro-organisms that establish small colonies for brief periods of time and then die off. We should be exposed to SBOs through interactions with soil and even the vegetables we eat. It is true that the commercialization of food has removed much of this contact from our modern lifestyles.

However, many adults have an even bigger problem: damaged resident flora (lactobacilli and bifidobacteria). This means that they don’t have the proper microbe makeup to interact with soil-based organisms in a healthy and beneficial way. SBOs are spore-forming, they reproduce differently than the beneficial bacteria that are normally part of our flora, and if a person doesn’t have healthy colonies of resident bacteria to keep the soil-based organisms in check, the SBOs can proliferate very rapidly, take over the gut and even become pathogenic. In fact, this poses such a risk that our manufacturing facility considers SBOs to be a contaminant and takes every precaution to ensure they stay out of our facility. Unlike resident probiotics, SBOs are so resistant that they will survive your stomach acids – making them increasingly popular as probiotic supplements.

Hyperbiotics PRO-15 is focused on repopulating the gut of those of us who have damaged our resident bacterial makeup through things like the modern diet high in processed and non plant-based foods, chlorine in our water supply and overexposure to antibiotics (either as medicine or in our food supply).

Once you have strong colonies of resident flora and a healthy GI tract, we absolutely recommend increased exposure to SBO’s… ideally by interacting more with nature (eating freshly grown, organic fruits and vegetables or even gardening, playing in the dirt or just being outside). If a more nature-based lifestyle isn’t an option, SBO supplementation may at that point be a good idea. As a disclaimer, it is our opinion that SBOs should not fall under the category of “probiotics” as it leads to confusion and misinformation.

Tips for Storage and Use

Store in a cool, dry place. Really. If you don’t live in a cool, dry place, it is best to store your bottle in the fridge or even better, in the freezer, when you can. This applies to any probiotic product – especially those in capsules or blister packs. With PRO-15, we guarantee the shelf life of our product with zero refrigeration – but, as a general rule, you will maximize the potency of any probiotic product by storing appropriately. And we are all about delivering you the maximum effect!


Take on an empty stomach in the AM. Our patented technology ensures that the living organisms are delivered throughout your day and throughout your gut – so you don’t need to buffer it with food as you may with capsules.

Use earlier rather than later. The reason we only sell a maximum of 60 tablets per bottle is that CFU’s begin to slowly die off once probiotic packaging is opened (this applies to all probiotics, not just PRO-15. In fact, our patented technology makes our die off significantly slower than that of others). And, even though our patented technology enables us to guarantee an effective dose until the best by date (unlike most other brands), we want you to get the highest potency possible. The negative, you have to reorder more frequently – but we promise, your gut will thank you!

Increase your Dosage when needed. If you are having digestive related issues or have just completed a round of antibiotics, you can take 3-5 pearls each morning for more intense repair. It’s also a good idea to increase your dosage just before and during travel as it often exposes you to added digestive and immune stress.


hyperbiotics PRO-15 label



At Hyperbiotics, our goal is to empower you with knowledge that leads to true gut health.
Read more about achieving and maintaining digestive health.


+ At the time of manufacture.
++ Patented BIO-tract® delivery technology consistently delivers as many as 15 times, or more, the number of live, viable probiotic organisms past simulated stomach acids than (plain/standard) capsules as repeatedly demonstrated through in vitro lab testing.

Feeling Your best starts with your gut.