PRO-15 Advanced Strength

Time Released with 15 Billion CFU & Kiwifruit

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  • GET 15 TIMES MORE RESULTS THAN WITH CAPSULES. With a superior patented delivery method, the probiotic organisms in this formula are released over an 8-10 hour period so they bypass your stomach acids and reach deep into your intestinal tract alive (where they are needed most) so you can finally experience the full benefits that probiotics have to offer.

    EXPERIENCE DIGESTIVE RELIEF. This triple strength formula provides targeted support for occasional digestive issues, helps keep you regular without overstimulation, and improves transit time for bowel movements. We added Kiwifruit powder, a superfruit ingredient that promotes colon health while helping your probiotics colonize within your intestinal tract. Kiwifruit powder naturally includes prebiotics, polyphenols, a kiwi-unique enzyme called actinidin, and insoluble fiber.

    LIVE MORE HEALTHY DAYS. 80% of your immune system is in your gut, and when probiotics (the good guys) are abundant in your body, it becomes harder for the bad guys to settle in. PRO-15 Advanced Strength helps restore beneficial bacteria for optimal digestive and immune health, helps balance yeast growth, and promotes daily relief from gas, bloating and irregularity. Life should be easy.

    LIFT YOUR MOOD AND ENERGY LEVELS. Fatigue and irritability are often a result of poor vitamin and mineral absorption. PRO-15 Advanced Strength helps create a microenvironment inside your digestive system that promotes full nutrient absorption so you can finally feel like your happy, energetic and vibrant self.

    PRO-15 Advanced

    SUPPORT YOUR IDEAL BODY WEIGHT. Did you know that scientists can predict whether people are fat or thin more effectively from their bacterial makeup (90 percent accuracy) than from their genes (58 percent accuracy)? It’s true. Research has made it clear that unhealthy gut flora can undermine even the best weight loss efforts. PRO-15 will help you get your gut back into equilibrium so your waistline can follow.

  • 15 Targeted Probiotic Strains (including Lactobacillus, Bifidobacterium and Streptococcus) to effectively counter the indiscriminate effects of today's broad spectrum antibiotics and other lifestyle choices that can deplete the microbiome.

    Kiwifruit Powder is a whole food superfruit ingredient, derived entirely from the New Zealand kiwifruit, that naturally supports regularity and promotes colon health while helping your probiotics colonize and take up permanent residence within your intestinal tract.

    Only Once per Day. That’s it. Because with time-release delivery, the full benefits are being delivered deep inside your gut hour by hour.

    Made in the USA. Our probiotics are homegrown with care in Washington state, then tableted in Colorado in a facility that is GMP certified through NSF. We adhere to the strictest quality control and FDA guidelines and perform rigorous testing on every lot to ensure they are effective and as the label states.

    15 Billion Colony Forming Units per BIO-tract® tablet which is equivalent to 225 Billion CFU (colony forming units) of normal probiotic capsules!

    Long Shelf Life & No Refrigeration Necessary. With the patented LiveBac® manufacturing process, we offer a guaranteed, extended shelf life with zero refrigeration. Most probiotics don't provide a date of any kind because their organisms die so quickly after being manufactured.

    Natural Probiotic Supplement. At Hyperbiotics, we don't believe in artificial. Our formulas are vegetarian, non-GMO, and free of lactose, gluten, and yeast. There is also no soy, sugar, iron, nuts, artificial flavors, artificial colors, or preservatives.

    PRO-15 Advanced does not contain any strains that are not resident to the human gut, like Soil Based Organisms (SBOs) or active yeasts.

    The Science Behind the Superiority

    Hyperbiotics PRO-15 Advanced is 15x More Effective than Capsules.

    Let us explain…

    Gas, bloating, irregularity, weakened immune system, malabsorption of nutrients, yeast growth, and other health and digestive problems affect many of us on a regular basis.

    Probiotics help restore the beneficial gut bacteria that may have been depleted as a result of poor diet, the overuse of antibiotics, food poisoning, or environmental toxins and promote overall health and well-being.

    However, studies show that without protection most probiotics entering the stomach won't survive to reach optimal sites within the gastrointestinal tract. Powders, liquids, capsules, and even cultured dairy products retain only 4% of these sensitive organisms during passage through the stomach's harsh environment.

    The good news: with the patented BIO-tract® protection and time-release delivery, we have increased this number to a remarkable 60%.

    The BIO-tract® Difference

    When the tablet is moistened by gastric fluids, a gel matrix forms that creates a protective layer, shielding beneficial organisms from stomach acids and directing them to release later in their journey.

    Once inside the gastrointestinal tract, probiotics begin to release at consistent levels from the tablet core, delivering a potent percentage of our living organisms throughout the day and throughout your gut, traveling deep into your intestinal tract where they are needed most.

    This is the only controlled-release delivery available for probiotics on the market today and is patented in 31 countries (US Patent 8,007,777 and 7,150,623).

    Finally, you can experience the full benefits that probiotics have to offer!

    The 4 Pillars of Kiwifruit Powder

    Naturally comprised of prebiotics, polyphenols, a kiwi-unique enzyme called actinidin, and insoluble fiber, the four pillars of this simple yet nutritious ingredient work together to deliver powerful support in regard to gut health and wellness.

    The prebiotics serve as food and nourishment for probiotics, helping them colonize within your gut while the polyphenols act as powerful antioxidants further helping the probiotics adhere to your intestinal wall.

    Actinidin, the natural protease enzyme extracted from organic kiwifruit, supplements the enzyme activity within your gut, supporting your colon and enabling “business as usual.” This kiwi-unique enzyme is a powerful tool for naturally supporting regularity and digestive health.

    BIO-tract® vs. Enteric Coated and Veggie Capsules

    Most probiotic supplements are in veggie capsules, which offer no protection from a harsh stomach environment, meaning that many of the beneficial organisms do not survive long enough to deliver any benefit.

    Enteric coated probiotic capsules offer some protection from stomach acids with a few drawbacks. Most enteric coatings are made of a synthetic chemical that the capsule is then dipped into. In addition to unwanted added chemicals, the capsule contains air and the coating contains moisture that is detrimental to the probiotic organisms. You see, freeze-dried probiotic powder is ‘hygroscopic,’ meaning that it seeks out moisture. The beneficial flora will start wicking the moisture away from the air and the coating, which starts killing the living probiotics inside. Essentially, both veggie capsules and enteric coated capsules cause the living organisms inside to self-destruct, leading to a far less potent product.

    Instead of a coating or a capsule, we tablet our formulas using a patented manufacturing process called LiveBac® and a patented delivery method called BIO-tract®, which provide much better protection for the beneficial flora while on the shelf (as there is minimal air and moisture) and as the tablet travels through the harsh environment of your stomach acids. Simply put, this leads to a much more effective probiotic and exponentially greater health benefits for you. Furthermore, BIO-tract® ensures that the active organisms are released slowly over an 8-10 hour period while making the journey through the intestinal tract, successfully bypassing your stomach acids so that they can colonize in your small and large intestine, where you need them.

    Hyperbiotics formulas are naturally derived with a guaranteed, extended shelf life with zero refrigeration.

    † At the time of manufacture.

    ‡ Patented BIO-tract® delivery technology consistently delivers as many as 15 times, or more, the number of live, viable probiotic organisms past simulated stomach acids than (plain/standard) capsules as repeatedly demonstrated through in vitro lab testing.

  • A shelf life you can count on. We use a patented manufacturing process called LiveBac® that increases the stability of PRO-15 Advanced without refrigeration and enables us to guarantee its shelf life until the date of expiration found on the bottom of your bottle.

    Store in a cool, dry place. Really. If you don't live in a cool, dry place or keep your home below 78 degrees, it is best to store your bottle in the fridge or even better, in the freezer, when/if you can. PRO-15 Advanced Strength is only susceptible to extreme heat and humidity once the bottle has been opened (our probiotics are very well protected until then). PRO-15 Advanced Strength has a guaranteed, extended shelf life with zero refrigeration.

    It's OK to take on an empty stomach (though not required). Our patented BIO-tract® delivery process ensures that the living organisms are delivered throughout your day and throughout your gut – so you don't need to buffer it with food as you may with other capsules.

    Use earlier rather than later. The reason we never have too many tablets per bottle at Hyperbiotics is that CFUs begin to slowly die off once the bottle is opened (this applies to all probiotics, not just PRO-15 Advanced Strength. In fact, our patented technology makes our die-off drastically slower than that of others!). We want you to get the highest potency possible, so we simply don't pack hundreds of tablets into one bottle.

    Hyperbiotics PRO-15 Advanced

    Increase your dosage when needed. If you are in search of a more intense approach to promoting regularity and supporting your digestive health, you can take 2-3 tablets each day. It's also a good idea to increase your dosage just before and during travel as it often exposes you to temporary digestive and immune stress.

    Recycle your bottle when you're done. We're committed to minimizing our ecological footprint, and we'd love for you to join us by recycling your empty bottle whenever possible. In fact, we're taking action to reduce negative impacts on our planet's natural resources and improve ecosystems around the world.

    An additional tip is to eat a whole food diet, high in fruits and vegetables. Studies show that the microorganisms in our gut change relatively quickly based on the food we eat. Foods that are rich in prebiotics will also help your probiotics colonize and “set up shop” in your GI tract.

    When you combine a clean, whole diet with probiotic supplementation, you are giving your body the tools it needs to find its balance again. Make sure to stay hydrated and to stay as active as you can so that your body can move out the unnecessary as your probiotic colonies are being repopulated.

  • What strains are in PRO-15 Advanced Strength?
    PRO-15 Advanced Strength contains the following probiotic strains:
    • Lactobacillus plantarum
    • Lactobacillus fermentum
    • Lactobacillus acidophilus
    • Bifidobacterium infantis
    • Lactobacillus casei
    • Bifidobacterium longum
    • Lactobacillus rhamnosus
    • Bifidobacterium lactis
    • Lactobacillus reuteri
    • Lactobacillus salivarius
    • Lactobacillus paracasei
    • Lactobacillus gasseri
    • Bifidobacterium bifidum
    • Bifidobacterium breve
    • Streptococcus thermophilus

    Should I take PRO-15 Advanced Strength or PRO-15?
    If you are looking for more intense support or have recently completed a round of antibiotics, PRO-15 Advanced Strength may be a good choice for you. With 15 billion CFU, it’s triple the strength of PRO-15 and contains kiwifruit powder which acts as a prebiotic and further aids in digestion and regularity.

    What are the benefits of taking probiotics?
    Probiotics replenish the good bacteria in your gut and help keep you healthy by:
    • Aiding in digestion
    • Helping you absorb the nutrients from your food and vitamins
    • Strengthening your immune system
    • Increasing your energy levels
    • Supporting brain function and mental clarity
    • Promoting optimal body weight

    Buy Hyperbiotics

    What is kiwifruit powder?
    Kiwifruit powder is a whole food superfruit ingredient, derived entirely from the New Zealand kiwifruit. It naturally supports regularity and promotes colon health while helping your probiotics colonize within your intestinal tract. Recent studies even suggest that it can help increase the frequency of bowel movements - helping you get back to “business as usual.”

    What makes Hyperbiotics probiotic formulas unique?
    We use a patented time-release delivery method called BIO-tract® that protects the beneficial organisms from stomach acids so they make it deep within your intestinal tract alive, where they can set up shop and get to work at keeping you healthy. This delivery method also makes our formulas 15 times more effective than standard capsules and powders, allowing you to finally experience the full benefits that probiotics have to offer.

    What makes Hyperbiotics probiotics more effective?
    Our formulas deliver superior results because they meet these four criteria:
    • Survival on the shelf
    • Survival past stomach acid
    • The right strains (human resident strains as opposed to SBOs or active yeasts)
    • A variety of strains

    How quickly can I expect to feel a difference?
    Probiotics are much like vitamins, some people notice a difference almost immediately while others may need a few weeks or more. It’s also possible to simply notice a subtle shift in a healthier direction. From the day you start taking PRO-15, it gets to work colonizing and restoring balance in your digestive tract.

    How long should I take a probiotic?
    We believe that taking a probiotic on a daily basis is one of the most proactive things that you can do to support your immune and digestive health. Because aspects of modern life can continuously deplete the beneficial bacteria in the gut, we suggest taking probiotics daily over the course of several months or more.

    Do I need to refrigerate these?
    With patented LiveBac®, we are able to guarantee our formulas with zero refrigeration - so you can be confident that your probiotics are both potent and effective when you take them.

    Will my probiotics survive being shipped in the heat?
    Yes! LiveBac® enables our products to withstand extreme heat for up to 7 days – even longer if both seals are left intact.

    Need help understanding the microbiome?
    Check out our Microbiome Glossary to learn more about this world beneath the microscope.

    Have additional questions? We’ve got answers! View our complete FAQ list here!

  • We offer FREE standard shipping on all U.S,\. orders over $45. We offer FREE expedited shipping on all U.S. orders over $100.

    • Continental U.S. orders: We offer standard shipping for $4, which takes 1 business day for processing and 2-7 business days for shipping. We offer expedited shipping for $7, which takes 1 business day for processing and 2-5 business days for shipping.

    • All other U.S. orders (HI, AK, U.S. territories, and APO addresses): We offer standard shipping for $4, which takes 1 business day for processing and 3-7 business days for shipping. We offer expedited shipping for $7, which takes 1 business day for processing and 3-5 business days for shipping.

    • International Orders (outside of the USA): We offer a flat fee of $10 to the countries listed below. For countries not on the list, we can ship via USPS or DHL and the cost varies by country. Please note we are not responsible for customs clearance in your country. Please check your local requirements before placing your order.

    Great Britain
    New Zealand

    We offer a 100% Satisfaction Guarantee or your money back!


  • "I love this product. My CrossFit coach turned me onto it when I had antibiotics and wanted to prop up the ol' gut health, and it kept the diarrhea away. I use it regularly now and have zero complaints. I don't work with supplements unless I sense an effect.

    "The numbers and delivery media helped sell me on these; it's supposedly built to last longer in digestion before releasing the probiotics, and they have a compelling variety of strains. So many probiotics seem to lack real potency when it comes down to it, this one seems worth the money." - Kevin

    "I tell friends and family how wonderful your products are and how much they've helped me. My sensitive gut is less so after faithful use of your products. I can't wait to use the Glucose Support and am happy to report on my experiences. Ordinarily, I avoid adding businesses on FB but am more than happy to follow you." - Lina D.

    "I'm hugely impressed by this product and it seems to have made my problems disappear. I was having on-and-off issues with loose stools for almost a year. These issues have now completely resolved themselves. I even tried changing my diet and some other medicines before which didn't help. I've been wanting to gain weight & build muscle for a while, which has been difficult due to my issues, but now my body seems to function a lot better and I'm able to gain weight normally again. For me the difference was really night and day." - Daniel

    "I started taking these on 08/28/16. Prior to this I had been to the doctor and they did an abdominal/pelvis CT scan that came up clear. However, they wanted me to see a gastroenterologist. I am not one to take pills, I eat a healthy, paleo-friendly diet, limit gluten and actively exercise. A friend of mine recommended this product so I thought I'd order it and try it. I take one Hyperbiotics PRO-15 Advanced probiotic daily and have to say that it has truly helped with my digestion and uncomfortable, painful bloating. I feel better than I have in a long time. I would definitely order again and continue using in my daily routine. Thank you! This is a blessing in disguise." - Renee

    "I am still new to the product so I am still learning what all this product is doing for me. So far it has helped me become more regular. I have positive hopes that I will see more benefits in the near future. I do know I already love the company though! I have had several communications with them the last few days because I had a couple of questions and they answered each email within minutes and gave me tons of advice! They seem to really care about their customers." - Amazon Customer

    "Great product that works at a great price. Also, their customer service reps are second to none. It's a refreshing thing when you talk to a rep and they genuinely listen and care for their customers needs." - Ramon S.

    "I'm now my 3rd bottle! I'm energetic again! I'm regular again! My body is digesting food better! My stomach doesn't hurt when I drink milk! I've tried everything to get the results from this one product! Excellent and I recommend this to anyone!" - Lisa

    "Great product. I no longer need to use the restroom right after dinner. I can eat medium rare steaks with no problem. It helps me with my heartburn issues as well. I have been using it for a month and have noticed a major difference in my digestive system." - Dean

    "I love these probiotics! I make sure to take them every day and they make me feel amazing. They help my digestion and my overall health." - Kyla

    "I have used probiotics for years, but have never felt this good. This brand is great! I have much more energy and I'm clear headed. The fog has lifted. I will continue to buy on automatic delivery! Thank you." - Jkon

    "I have been using this product for the past year, and I must say, it is the most effective probiotic I have ever taken! Because of my diet, I have not had the healthiest digestive system and was terrorized with constant constipation. After some research, I decided to try taking probiotics. My sister has been taking these probiotics for months. She heard of my troubles and allowed me to try a week's worth. I am glad she did so! After a week, I was having regular bowel movements and no constipation. I was clear of any "backup" and felt all around great! I decided to purchase some myself to use on a daily basis and my health improved drastically over the year. I also decided to change my diet, and with the PRO-15 probiotics, I felt as healthy as I can be! The product is pricey for only 30 capsules (a month's supply, depending on intensive repair, or for continued use), but the relief is worth the dollar a day. I definitely recommend the PRO-15 Advanced Strength Probiotics!" - Thomas

    To read more of what our customers have to say, please visit our testimonial page!


    We are dedicated to you and your journey toward greater health.
    We expect you will love our formulas. If for some reason you don’t, you are protected by our no-questions-asked, money back guarantee!

    Our 100% Money Back Guarantee
    We will go above and beyond to help you however we can. Just say the word if you’re not fully satisfied—for any reason—and we’ll replace your bottle for another formula or we’ll fully refund your purchase. No questions asked.

    You have everything to gain and absolutely nothing to lose.

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